https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Proteomic and microscopic strategies towards the analysis of the cytoskeletal networks in major neuropsychiatric disorders https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29612 Wed 11 Apr 2018 15:53:45 AEST ]]> Cellular responses during morphological transformation in Azospirillum brasilense and its flcA knockout mutant https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:18830 Wed 11 Apr 2018 09:26:28 AEST ]]> Profilin-1 overexpression in MDA-MB-231 breast cancer cells is associated with alterations in proteomics biomarkers of cell proliferation, survival, and motility as revealed by global proteomics analyses https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19788 cell proliferation (FKPB1A, HDGF, MIF, PRDX1, TXNRD1, LGALS1, STMN1, LASP1, S100A11, S100A6), survival (HSPE1, HSPB1, HSPD1, HSPA5 and PPIA, YWHAZ, CFL1, NME1) and motility (CFL1, CORO1B, PFN2, PLS3, FLNA, FLNB, NME2, ARHGDIB). In view of the pleotropic effects of PFN1 overexpression in breast cancer cells as suggested by these new findings, we propose that PFN1-induced phenotypic changes in cancer cells involve multiple mechanisms. Our data reported here might also offer innovative strategies for identification and validation of novel therapeutic targets and companion diagnostics for persons with, or susceptibility to, breast cancer.]]> Sat 24 Mar 2018 07:57:13 AEDT ]]>